3-Pyridines as replacements for an isoxazole ring: The antirhinoviral activity of pyridine analogues related to disoxaril

Abstract In a series of rhinovirus inhibitors related to Disoxaril, replacement of 3-methylisoxazole with all 3 isomers of pyridine showed the 3-pyridyl isomer most similar to 3-methylisoxazole in spectrum of activity over 15 human rhinovirus serotypes.