0499: Predicting post-capillary origin of Pulmonary Hypertension (PH): external validation of the PH Council (PHC) of International Society for Heart and Lung Transplantation (ISHLT) score

Background Determination of the origin (pre or post-capillary) of PH is crucial to guide therapy. Right heart catheterization (RHC) is the gold standard to identify PH origin. However this technique is invasive and may cause complications. The PHC of ISHLT proposes a clinical and echocardiographic score to estimate the origin of PH in order to select patients who truly require RHC. The aim of the study was to evaluate the validity of this score in a real life population of patients with PH. Methods We studied retrospectively clinical, echocardiographic and hemodynamic characteristics of consecutive patients referred to our center to undergo a RHC between January 2005 and August 2013 and evaluated the performance of the PHC prediction score. Results 116 patients with pre capillary PH and 71 with post capillary PH were included.Post capillary PH patients were older(73.2 vs 62.8, p Conclusion The score proposed by the PHC of ISHLT to determine noninvasively the origin of PH is fairly accurate but could be enhanced by the adjunction of AF as a new criterion.