Abstract 11757: Telomerase Treatment Restores Transcriptional Profile and Epigenetic Landscape in Progeria Vascular Cells

Anahita Mojiri,Qiu Xu,Luay Boulahouache,Elisa Morales,Guangyu Wang,John P. Cooke

Abstract 11757: Telomerase Treatment Restores Transcriptional Profile and Epigenetic Landscape in Progeria Vascular Cells

2021

Anahita Mojiri
Qiu Xu
Luay Boulahouache
Elisa Morales
Guangyu Wang
John P. Cooke

Hutchinson-Gilford progeria syndrome (HGPS) is a model of accelerated vascular aging caused by a de novo mutation of a single nucleotide in the Lamin A gene. The accumulation of abnormal lamin A (p...

Keywords:

Cancer research
Gene
Progeria
Lamin
Epigenetics
Gene expression
Telomerase
Medicine
Vascular disease
Nucleotide

Correction
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