Paediatric prescribing of anti-asthmatics in primary care in Castilla-León. Geographical variability ,

Abstract Introduction and objectives Asthma is one of the most prevalent chronic diseases with effective treatment in paediatrics. The aim of this study is to describe the paediatric prescribing of anti-asthmatics in Castilla-Leon, analyzing its geographic variability and temporal evolution. Materials and methods An analysis was made of prescriptions dispensed in pharmacies of R03 therapeutic subgroup (anti-asthmatic agents), and the active ingredients mepyramine and ketotifen, prescribed in children less than 14 years of age in the Castilla-Leon health service from 2005 to 2010 in Primary Care. Data is presented in prescribed daily doses per thousand inhabitants per day (PDHD) for each active ingredient being calculated raw rates and age-adjusted to the variables health area, type of health zone and year of study. Results A total of 462,354 prescriptions of anti-asthmatic agents were dispensed to a population of 1,580,229 persons/year. There was wide variation between areas in the type and intensity of anti-asthmatic agents used, partly explained by differences in the prevalence of asthma. Montelukast predominated as controller drug in most of them (PDHD 3.1–7.7), being similar the consumption intensity in the three types of health zones (PDHD 4.7–4.8). The annual variability was low. Conclusions The study describes the paediatric prescribing pattern of anti-asthmatic agents in Castilla-Leon between 2005 and 2010. It shows wide geographical variation, as well as inadequacies regarding current recommendations of asthma treatment.