Ultrastructural, cytochemical, and microchemical observations on cytomegalovirus (salivary gland virus) infection of human cells in tissue culture☆

Abstract The cytoplasmic body that forms, in addition to the nuclear inclusion, in cells infected with cytomegalovirus has been shown to be an aggregate of lysosomes. These lysosomes appear and surround viruses as they are released from the nucleus. The extent of inactivation of the virus remains to be determined. The outer of the two coats of CMV is derived from the inner nuclear membrane during the exodus of the virus from the nucleus.