Pemphigus foliaceus in a child responded to flucloxacillin therapy: Case report

Abstract Pemphigus foliaceus is a rare autoimmune blistering disease comprising two major types: endemic and sporadic. The endemic form, also known as fogo selvagem, affects children and young adults in rural Brazil while the sporadic form generally affects the middle-aged and the elderly. Here we report a sporadic form of pemphigus foliaceus in a child in which the skin eruption responded to flucloxacillin. Upon discontinuation of flucloxacillin, lesions reappeared and then cleared upon resuming the antibiotic. Dapsone was thereafter administered with good control.