Cold-knife conization versus loop excision: histopathologic and clinical results of a randomized trial.

Abstract Ninety patients with cervical intraepithelial neoplasia (CIN) were randomly assigned to loop excision ( n = 38) or cold-knife conization ( n = 52). All specimens were well evaluable at histology. The average width of the lesions at histology was 10.2 and 9.7 mm, respectively (ns). The average weight of the specimens was 2.6 and 5.6 g ( P P P