The Protective Role of HLA-DRB1∗13 in Autoimmune Diseases

Andreia Bettencourt,Cláudia Carvalho,Bárbara Leal,Sandra Brás,Dina Lopes,Ana Martins da Silva,Ernestina Santos,Tiago Torres,Isabel Almeida,Fátima Farinha,Paulo Barbosa,António Marinho,Manuela Selores,João R. Correia,Carlos Vasconcelos,Paulo Costa,Berta Martins da Silva

The Protective Role of HLA-DRB1∗13 in Autoimmune Diseases

2015

Andreia Bettencourt
Cláudia Carvalho
Bárbara Leal
Sandra Brás
Dina Lopes
Ana Martins da Silva
Ernestina Santos
Tiago Torres
Isabel Almeida
Fátima Farinha
Paulo Barbosa
António Marinho
Manuela Selores
João R. Correia
Carlos Vasconcelos
Paulo Costa
Berta Martins da Silva

Autoimmune diseases (AIDs) are characterized by a multifactorial aetiology and a complex genetic background, with the MHC region playing a major role. We genotyped for HLA-DRB1 locus 1228 patients with AIDs-213 with Systemic Lupus Erythematosus (SLE), 166 with Psoriasis or Psoriatic Arthritis (Ps

Keywords:

Psoriasis
Immunology
Lupus erythematosus
HLA-DRB1
Rheumatology
Allele
Psoriatic arthritis
Major histocompatibility complex
Biology
Human leukocyte antigen
Internal medicine
Medical genetics
Medicine

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