EPR study of dosimetric properties of glucose irradiated by X-photons and electrons: Analyse of storage effect on produced free radicals

2018 
Abstract Electron Paramagnetic Resonance “EPR” measurements were undertaken on powder glucose irradiated by X photons and electrons in order to study its dosimetric properties and evaluate its spectral behaviour in the field of radiotherapy. Dose-response evolution and the impact of storage on irradiated samples were analysed using peak to peak amplitude and double integration method. The obtained measurable threshold dose is 2 Gy. The dependence of the EPR signal as function of the absorbed dose was found to be linear in the dose range 0 – 20 Gy for all used energies. An effect of the type of radiation on the sensitivity is observed, glucose seems to be slightly more sensitive to X photons irradiation than to electrons. The investigations of shape and intensity of EPR signals during storage period of twelve months revealed a consequent radical activity, probably due to two major free radicals produced by irradiation. The signal height of one of the EPR components increases significantly during the first two months after irradiation, and then stabilizes.
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