PP.27.11: STRUCTURAL AND FUNCTIONAL ALTERATIONS IN CEREBRAL AND MESENTERIC SMALL RESISTANCE ARTERIES FROM CONGENIC LINES FOR A MAJOR STROKE QTL ON RAT CHROMOSOME 1 AFTER HIGH SALT DIET

C. De Ciuceis,Claudia Rossini,Enzo Porteri,Speranza Rubattu,Maria Cotugno,Rosita Stanzione,Michele Madonna,Claudia Agabiti-Rosei,E. La Boria,Annamaria Sarkar,Alice Gavazzi,Beatrice Petroboni,Massimo Volpe,Enrico Agabiti-Rosei,D Rizzoni

PP.27.11: STRUCTURAL AND FUNCTIONAL ALTERATIONS IN CEREBRAL AND MESENTERIC SMALL RESISTANCE ARTERIES FROM CONGENIC LINES FOR A MAJOR STROKE QTL ON RAT CHROMOSOME 1 AFTER HIGH SALT DIET

2015

C. De Ciuceis
Claudia Rossini
Enzo Porteri
Speranza Rubattu
Maria Cotugno
Rosita Stanzione
Michele Madonna
Claudia Agabiti-Rosei
E. La Boria
Annamaria Sarkar
Alice Gavazzi
Beatrice Petroboni
Massimo Volpe
Enrico Agabiti-Rosei
D Rizzoni

Objective:A quantitative trait locus (QTL) for stroke proneness between the kallikrein (Klk) and Mt1pa markers on rat chromosome 1 was previously identified, and to gain functional insights, congenic strains were constructed by introgressing a selected chromosomal segment from the stroke-prone (SHRs

Keywords:

Stroke
Quantitative trait locus
Internal medicine
Diabetes mellitus
Endocrinology
Congenic
Chromosome
Medicine
Kallikrein
salt diet

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