Comparative study of the DNA damage in three tissues of blue mussel(Mytilus edulis) after exposure to three typical POPs

In this article,we compared the DNA damage in blue mussel gill,gonad and digestive gland cells that were exposed to Aroclor1254、BaP and DDT by comet assay.The results show that tail DNA% was a perfect parameter for DNA damage.In addition,there were significant time-and dose-dependent damage to the gill,gonad and digestive gland cells of blue mussel.Furthermore,the toxic effect of BaP was much more than the other two POPs;and gill and digestive gland cells were much more sensitive than gonad cells for the POPs toxicity.We also discussed the reason underlining the toxic sensitivity of different tissues and the significance of monitoring POPs in marine ecosystem.The results are helpful for assessing the toxic effects and exploring the toxicological mechanism of POPs.