Michael Addition of Selenoamides to α,β-Unsaturated Carbonyl Compounds: Stereocontrolled Synthesis of δ-Oxo Selenoamides and Their Reactivity

Lithium eneselenolates generated from selenoamides underwent Michael addition to α,β-unsaturated esters and ketones with high diastereoselectivity to give δ-oxo selenoamides in moderate to high yields within a few seconds. Further selective transformations of the δ-oxo selenoamides were also achieved.