280. The risk factors of respiratory complications after posterior spine deformity surgery for patients with early onset scoliosis

BACKGROUND CONTEXT Early onset scoliosis (EOS) is associated with high morbidity and some of them require posterior spine deformity surgery (PSDS). Respiratory complications following PSDS are common, and have been reported in 15.6% to 28.2% of operative cases. Postoperative complications following PSDS may cause further impairment of respiratory function, leading to prolonged intubation time, need for reintubation, and longer inpatient hospital stay. PURPOSE We assumed that there were preoperative laboratory values and patient factors that are associated with postoperative respiratory complications (RCs) in EOS populations undergoing PSDS. To determine the risk factors of RC in EOS undergoing PSDS. STUDY DESIGN/SETTING A retrospective analysis with prospective outcomes research. PATIENT SAMPLE All patients who underwent PSDS for EOS in a single institute from 2008-2018. OUTCOME MEASURES Preoperative laboratory values for transferrin, prealbumin, hemoglobin/hematocrit, total protein, albumin, total lymphocyte count and blood loss to total blood volume ratio (BL/TBV) were collected. METHODS The spine surgery database was reviewed to identify all patients who underwent PSDS for EOS in a single institute from 2008-2018. RC was defined as postoperative pneumonia, pleural effusion, pneumothorax, need for reintubation, respiratory status requiring a return to the intensive care unit, or prolonged (>4-day) need for mechanical ventilation. Preoperative laboratory values for transferrin, prealbumin, hemoglobin/hematocrit, total protein, albumin, total lymphocyte count and blood loss to total blood volume ratio (BL/TBV) were collected. RESULTS There were 76 patients included in our study. Results of single-factor comparison demonstrated that the following seven variables were statistically different (P 15% (X9). The multi-factor unconditional logistic regression analysis revealed that X8 (OR=49.322), X9 (OR=18.423), X5 (OR= 11.883), and X6 (OR=8.769) were independent and positively correlated with the RC. CONCLUSIONS Albumin  15%, history of pneumonia and transferrin  FDA DEVICE/DRUG STATUS This abstract does not discuss or include any applicable devices or drugs.