Effect of tryptase inhibition on joint inflammation: a pharmacological and lentivirus-mediated gene transfer study
2017
Background
Increasing evidences indicate that an unbalance between tryptases and their endogenous inhibitors, leading to an increased proteolytic activity, is implicated in the pathophysiology of rheumatoid arthritis. The aim of the present study was to evaluate the impact of tryptase inhibition on experimental arthritis.
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