Magnetic Ligation Method for Quantitative Detection of MicroRNAs

Monty Liong,Hyungsoon Im,Maulik D. Majmudar,Aaron D. Aguirre,Matthew Sebas,Hakho Lee,Ralph Weissleder

Magnetic Ligation Method for Quantitative Detection of MicroRNAs

2014

Monty Liong
Hyungsoon Im
Maulik D. Majmudar
Aaron D. Aguirre
Matthew Sebas
Hakho Lee
Ralph Weissleder

A magnetic ligation method is utilized for the detection of microRNAs amongst a complex biological background without polymerase chain reaction or nucleotide modification. The sandwich probes assay can be adapted to analyze a panel of microRNAs associated with cardiovascular diseases in heart tissue samples.

Keywords:

Nucleic acid amplification technique
microRNA
Ligation
Microsphere
Biology
Polymerase chain reaction
Biochemistry
Magnetite Nanoparticles
Molecular Probe Techniques

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