Changes in carbohydrate metabolism indices in patients with hemorrhagic fever associated with renal syndrome

: Metabolism of carbohydrates was impaired in 80 patients with hemorrhagic fever accompanied by renal syndrome, in which activation of glycolysis occurred due to a decrease in aerobic oxidation and development of metabolic acidosis. Lactacidemia and activation of LDH in blood serum were considered as criteria of the degree of hypoxia and of the severity of the disease. Estimation of lactate and pyruvate in blood serum and urine might be used for diagnosis and for evaluation of the treatment efficiency.