466 INTERLEUKIN-28B rs12979860 C ALLELE IS PROTECTIVE AGAINST ADVANCED FIBROSIS IN CHRONIC HEPATITIS C GENOTYPE 1 INFECTION: ANALYSIS OF THE AUSTRALASIAN CHARIOT STUDY COHORT

465 POTENTIAL ECONOMIC IMPACT OF APPLYING ONUBA SCALE: A NOVEL PROGNOSTIC MODEL OF RESPONSE IN CHRONIC HEPATITIS C GENOTYPE 1 F.M. Jimenez Macias, M. Ramos Lora, F. Barrero Alor, L. Galisteo Almeda, C. Ruiz-Frutos, E. Pujol de la Llave, S. Grutzmancher Saiz, M.V. Salinas-Martin, J.L. Robles Rodriguez, S. RodriguezNovoa, E. Alvarez Barco, M. Prada Pena, A. Camacho, M.A.N. Fabis, Consejeria de Salud, Junta de Andalucia, Huelva. Department of Hepatology, Department of Biochemistry and Molecular Biology, Juan Ramon Jimenez Hospital, Experimental Research Department, Huelva University, Department of Internal Medicine, Department of Pharmacology, Division of Clinical Pathology, Juan Ramon Jimenez Hospital, Huelva, Molecular Biology Laboratory, Department of Infectious Diseases, Carlos III Hospital and Foundation of Research, Madrid, Department of Documentation and Statistics, Juan Ramon Jimenez Hospital, Fundacion Andaluza Beturia para la Investigacion en Salud, FABIS, Huelva, Spain E-mail: ferjimenez2@gmail.com