Role of IL-4 in Cytokine Storm Syndrome due to COVID-19 Infection

SARS-CoV-2 that causes Coronavirus disease 2019 (COVID-19) is a spreading global threat. COVID-19 declared as a pandemic by the WHO. COVID-19 is transmitted by direct contact or droplets and can infect the respiratory tract which resulting in acute respiratory distress syndrome (ARDS) and pneumonia in most of cases. IL-4 as a Th2 cytokines has different roles in coronaviruses infections. In this article we focused on function of IL-4 in COVID-19.