Reducing Clostridium difficile Colitis Rates Via Cost-Saving Diagnostic Stewardship

We conducted a quality improvement project at a large public tertiary-care academic hospital to reduce reported hospital-acquired Clostridium difficile infection (CDI) rates. We introduced diagnostic stewardship and provider education, resulting in a 2-fold reduction in C. difficile nucleic acid amplification test (NAAT) orders and markedly lower hospital CDI rate. Infect Control Hosp Epidemiol 2018;39:734–736