Research progress of proteomics and prediction of metastasis and recurrence in hepatocellular carcinoma

Tumor metastasis and recurrence had become a key to curative effect and long-term survival,and it's hotspot of current clinical oncology research.Differential expression of proteomics between cancer and normal tissue can be used for discovering new tumor markers.Clinical detection of liver cancer-related protein molecules was useful to monitor and assess early diagnosis,recurrence and prognosis of hepatocellular carcinoma.Herein,this article reviewed the research progression of protein molecules in hepatocellular carcinoma. Key words: Liver neoplasms ;  Proteomics ;  Biological markers ;  Neoplasm metastasis ;  Recurrence ;