Hydroxylamine analogs of 2,6 di-t-butylphenols: Dual inhibitors of cyclooxygenase and 5-lipoxygenase or selective 5-lipoxygenase inhibitors

James B. Kramer,Thomas Capiris,Jagadish C. Sircar,David T. Connor,Dirk A. Bornemeier,Richard D. Dyer,Paul J. Kuipers,John A. Kennedy,Clifford D. Wright,Godwin C.N. Okonkwo,Mark E. Lesch,Denis J. Schrier,Diane H. Boschelli

Hydroxylamine analogs of 2,6 di-t-butylphenols: Dual inhibitors of cyclooxygenase and 5-lipoxygenase or selective 5-lipoxygenase inhibitors

1995

James B. Kramer
Thomas Capiris
Jagadish C. Sircar
David T. Connor
Dirk A. Bornemeier
Richard D. Dyer
Paul J. Kuipers
John A. Kennedy
Clifford D. Wright
Godwin C.N. Okonkwo
Mark E. Lesch
Denis J. Schrier
Diane H. Boschelli

Abstract The preparation of hydroxylamine analogs of 2,6-di- tert -butylphenols (DTBP) and the inhibition of cyclooxygenase (CO) and 5-lipoxygenase (5-LO) by these compounds is discussed.

Keywords:

Hydroxylamine
Arachidonate 5-lipoxygenase
Organic chemistry
Biochemistry
Cyclooxygenase
Chemistry
Stereochemistry

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations