Prospective Economic Evaluation of a Peer Support Intervention for Prevention of Postpartum Depression among High-Risk Women in Ontario, Canada

Objective  A previous multisite, randomized, controlled trial of peer support compared with usual care for prevention of postpartum depression demonstrated a reduction in depression symptoms at 12 weeks postbirth. Our objective was to determine the cost-effectiveness of this intervention. Study Design  Prospectively planned economic evaluation alongside the clinical trial to determine the cost per case of postpartum depression averted, using individual patient data ( n  = 610) and societal perspective. All costs were expressed in 2011 Canadian dollars. Results  The mean cost per woman was $4,497 in the peer support group and $3,380 in the usual care group (difference of $1,117, p Conclusions  Although this is a volunteer-based program, it results in a net cost to the health care system and society. However, this cost is within the range for other accepted interventions for this population.