Linezolid Resistance in Brazilian Staphylococcus hominis Strains Is Associated with L3 and 23S rRNA Ribosomal Mutations

Lara M. de Almeida,Maria Rita E. de Araújo,Andrey G. Sacramento,Mónica Pavez,Alinne G. de Souza,Fernanda Rodrigues,Ana C. Gales,Nilton Lincopan,Jorge Luiz Mello Sampaio,Elsa Masae Mamizuka

Linezolid Resistance in Brazilian Staphylococcus hominis Strains Is Associated with L3 and 23S rRNA Ribosomal Mutations

2013

Lara M. de Almeida
Maria Rita E. de Araújo
Andrey G. Sacramento
Mónica Pavez
Alinne G. de Souza
Fernanda Rodrigues
Ana C. Gales
Nilton Lincopan
Jorge Luiz Mello Sampaio
Elsa Masae Mamizuka

Among different clinical staphylococcal strains, linezolid resistance has been mainly mediated by mutations in the central loop of domain V of 23S rRNA, with the G2576T mutation being the most prevalent.…

Keywords:

Linezolid
Microbiology
Virology
23S ribosomal RNA
Ribosomal RNA
Ribosomal protein
Staphylococcus hominis
Mutation
Biology
Ribosome
Staphylococcal infections
linezolid resistance

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