A novel water soluble octaazamacrocyclic dinuclear copper(II) complex with tetra-pendant arms: Crystal structure and SOD activity

Abstract A novel water-soluble octaazamacrocyclic dinuclear copper(II) complex with tetra-pendant arms, [Cu 2 L] Cl 2 ∙ 5H 2 O, was synthesized by [2+2] condensation between 2, 6-diformyl-4-chlorophenol and N, N, N', N'-tetrakis(2'-aminoethyl)-1, 2-diaminopropane in the presence of Cu(OAc) 2 ·H 2 O. Single-crystal X-ray structural analysis reveals that every copper(II) adopts a trigonal bipyramid coordination configuration. Macrocyclic units are joined together by strong π – π stacking interaction with centroid–centroid distance of 3.658 A. Water pentamers with O–O distances of 2.099–2.841 A are observed in the complex. The activity of superoxide dismutase of the complex has been investigated by the nitro blue tetrazolium method.