Sox2 is required for olfactory pit formation and olfactory neurogenesis through BMP restriction and Hes5 upregulation

Tamilarasan K. Panaliappan,Walter Wittmann,Vijay K. Jidigam,Sara Mercurio,Jessica Bertolini,Soufien Sghari,Raj Bose,Cedric Patthey,Silvia K. Nicolis,Lena Gunhaga

Sox2 is required for olfactory pit formation and olfactory neurogenesis through BMP restriction and Hes5 upregulation

2018

Tamilarasan K. Panaliappan
Walter Wittmann
Vijay K. Jidigam
Sara Mercurio
Jessica Bertolini
Soufien Sghari
Raj Bose
Cedric Patthey
Silvia K. Nicolis
Lena Gunhaga

The transcription factor Sox2 is necessary to maintain pluripotency of embryonic stem cells, and to regulate neural development. Neurogenesis in the vertebrate olfactory epithelium persists from em ...

Keywords:

Olfactory epithelium
Genetics
Cell biology
Transcription factor
SOX2
Developmental biology
Neural development
Biology
Downregulation and upregulation
Neurogenesis
Embryonic stem cell
Bone morphogenetic protein
Olfactory mucosa
HES5

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