Computer analysis of the dynamics of two tumor foci with respect to circulating immune cells
1991
: A mathematical model of the bilocal immunogenic tumors was analysed by a computer. An increase of the intensity or/and growth of asymmetry in cytotoxic cells migration between two tumor centres could lead to bifurcations in the system. This approach allows interpretation of a number of paradoxes in the interrelations between the original tumor and metastases.
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