Regression of an HCV-associated disseminated marginal zone lymphoma under IFN-free antiviral treatment.

To the editor: Hepatitis C virus (HCV) is prevalent in B-cell–associated lymphomas, including marginal zone and diffuse large B-cell lymphomas.[1][1] A stepwise model of lymphomagenesis induced by chronic antigenic stimulation and/or a direct pro-oncogenic effect of intracellular HCV proteins is