Diketopiperazines from Marine Isolate of Actinobacterium Nocardiopsis umidischolae KMM 7036

In continuation of research on secondary metabolites of marine isolates of microorganisms [1, 2], we investigated actinobacterium Nocardiopsis umidischolae KMM 7036, which was isolated from Mycale sp. fungi, collected in Deryugin Basin, Sea of Okhotsk. The actinobacterium was cultivated and the culture was processed as described earlier [3]. Multiple column chromatography over silica gel using a gradient of hexane EtOAc (100% hexane 100% EtOAc) of the culture extract isolated 1 (11.4 mg), 2 (0.9 mg), and 3 (2.2 mg).