Development of PCR‐SSOP for the identification of HLA‐A*02 subtypes and determination of HLA‐A*02 frequencies within different ethnic populations
1997
A PCR-SSOP typing method, involving a single PCR amplification in conjunction with 19 digoxigenin labelled oligonucleotide probes, has been developed for the identification of 17 known HLA-A*02 alleles. The method has been applied to four populations (Northern Ireland, Singapore Chinese, Shetland Island and Mexican) and percentages of HLA-A*02 alleles determined within each population.
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