Diagnostic Value of Brain Tumor Neuroendoscopic Biopsy andCorrelation with Open Tumor Resection
2014
Background The risks of stereotactic biopsy are increased not
only in tumors located in the vicinity of vascular structures,
but also in cystic, intraventricular, and periventricular
lesions. The use of neuroendoscopy for cystic,
intraventricular, or periventricular brain tumors is
particularly advantageous because of the possibility of biopsy
and immediate hemostasis under direct vision. Neuroendoscopy
provides the possibility of controlling tumor-associated
obstructive hydrocephalus by means of endoscopic third
ventriculostomy or septostomy. The literature gives good
evidence for the diagnostic benefits of neuroendoscopic biopsy.
The correlation of the histology obtained by neuroendoscopic
biopsy and subsequent surgical resection may allow the
evaluation of the validity of diagnostic neuroendoscopic
biopsy. Materials and Methods Between 2003 and 2010, 23
patients with suspected cystic brain tumor (12 males; age
range, 21-75 years; mean age, 49.7 years; and 11 females; age
range, 22-76 years; mean age, 59.1 years) and 35 patients with
intraventricular or periventricular brain tumors (19 males; age
range, 6-80 years; mean age, 43.9 years; and 16 females; age
range, 11-78 years; mean age, 46.2 years) underwent navigated
neuroendoscopic biopsy. Results Diagnostic samples were
obtained in all cystic tumors and in 94.7% of intraventricular
or periventricular tumors. Tumor resection after
neuroendoscopic biopsy was performed in seven patients with
cystic tumors. The results of the histological analysis of
samples taken during endoscopic biopsy and surgical resection
were identical in five of these patients (70.1%). Four patients
with intraventricular or periventricular tumors underwent tumor
resection after neuroendoscopic biopsy. The histological
results of neuroendoscopic biopsy and tumor resection were
identical in three patients (75%). Neuroendoscopic biopsy was
performed in six patients with expansive pseudocyst after tumor
resection and oncological therapy. The results of the
neuroendoscopic biopsy matched the results of open surgery in
four patients (66%). In the two remaining patients, there was a
difference in tumor grading. Conclusion The diagnostic accuracy
of neuroendoscopic biopsy samples can be compared with the
results of stereotactic biopsy. The histological results of
endoscopically taken biopsy samples and the final histological
results obtained during open surgery correlate in the majority
of patients, and underlines the high diagnostic validity of
neuroendoscopic biopsy.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
0
References
0
Citations
NaN
KQI