Human papillomavirus (HPV) in laryngeal leukoplakia

: Epidemiological data and results of molecular studies suggest that human papillomavirus could be considered a risk factor for the upper respiratory tract cancers. HPV infection plays also the important role in the laryngeal precancerous states. Six out of 16 studied cases of laryngeal leukoplakia revealed presence of HPV DNA (37.5%). In situ hybridisation technique was used for the detection of viral DNA.