Inhibition of Th17 differentiation by anti-TNF-alpha therapy in uveitis patients with Behçet's disease

Sunao Sugita,Yuko Kawazoe,Ayano Imai,Yukiko Yamada,Shintaro Horie,Manabu Mochizuki

Inhibition of Th17 differentiation by anti-TNF-alpha therapy in uveitis patients with Behçet's disease

2012

Sunao Sugita
Yuko Kawazoe
Ayano Imai
Yukiko Yamada
Shintaro Horie
Manabu Mochizuki

Introduction The purpose of this study was to determine whether anti-tumour necrosis factor alpha (anti-TNF-α) antibody, infliximab, can inhibit T helper 17 (Th17) differentiation in uveitis patients who have Behcet's disease (BD).

Keywords:

Immunology
Antibody
Behcet's disease
Necrosis
Tumor necrosis factor alpha
Rheumatology
Infliximab
Internal medicine
Uveitis
Alpha (ethology)
Medicine
RAR-related orphan receptor gamma
Cluster of differentiation
CD3
CD28
Proinflammatory cytokine

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