Synthesis and Antitumor Evaluation of Analogues of the Marine Pyrroloiminoquinone Tsitsikammamines.
2010
Two series of analogues of the marine pyrroloiminoquinone alkaloids tsitsikammamine have been synthesized on the basis of a Michael addition between 2'-amino-1-(4-methoxyphenyl)-ethanol and two indolediones. All the compounds were evaluated in vitro for antiproliferative activity against distinct cancer cell lines.
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