Enormous ventricular septal defect with pulmonary hypertension in infants during the peroperation time

Objective To summerize the experiences of operation and postoperative treatment of huge ventricular septal detect(VSD) in infants. Methods One hundred and fifty two infants with large VSD underwent surgical repalrment under hypothermie extracorporeal circulation from Januany 1998 to January 2006 . The other complicated malformations were rectified during the op-eration. Results Three patients died from low cardiac out - put with the hospital mortitity of 4.61%. The incidence of complica-tions was 12.5%. One case had Ⅲ degree - AVB that recovered sinus rhythmia 8 days later through settled artifical cardiac pa-cing and pumped into perenaline; three cases had a residual shunting that was only 1 or 2 millimetre estimated by color ultrasonic.The mechanical ventrilation time ranged from 10 to 96 hours [mean(12±8)h]. Follow - up visits of 143 cases from 1 to 7 yearsshowed that their growth got better very much. Conclusion Large VSD repairment should be performed as early as possible for infants with pulmonary hypertension and repeated pulmonary infection or heart failure that is not easy to be corrected by physi-cian. The out - come is satisful, meanwhile. It is important to enhance myocadical protection and do a perfect postoperative treat-ment in order to decrease the hospital mortality. Key words: Infants;  Ventricular septal defect;  Pulmonary hypertension;  Surgical treatment