Fibroadenoma of the breast with florid epithelial cells hyperplasia: a case report
2015
Fibroadenoma is a benign biphasic tumor of the breast, composed of an epithelial and a stroma component. Fibroadenoma with epithelial cells hyperplasia may contribute to the higher risk of breast cancer , especially for florid and atypical hyperplasia . The distinction between fibroadenoma with florid epithelial cells hyperplasia, in-situ carcinoma and invasive duct carcinoma of the breast ban be difficult morphologically. To solve the problem , immunohistochemical staining with specific andibodies will be helpfull in distinguishing usual duct hyperplasia from ductal carcinoma in situ . A case of fibroadenoma with florid epithelial cells hyperplasia has been reported. Morphologically, this tumor is difficult to be differentiated from ductal carcinoma . Immunohistochemical staining with High molecular weight cytokeratins 34BE12, Smooth Muscle Actin (SMA),E-cadherin could be used to determine the diagnosis of this tumor.
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