Angioid streaks in identical twins

Angioid streaks were first described in 1889 by Doyne,1 who described them in a patient with retinal haemorrhages secondary to trauma. Knapp2 first coined the term “angioid streaks” although it was Kopler, in 1917, who correctly determined that angioid streaks represented changes at the level of Bruch’s membrane. Since then, angioid streaks have been described in a diverse group of diseases including pseudoxanthoma elasticum, Paget’s disease, and the haemoglobinopathies such as sickle cell anaemia and β thalassaemia.3 Although angioid streaks have been reported among siblings and family members in association with pseudoxanthoma elasticum, they have not previously been reported in identical twins …