Compositions and methods for treating hair loss using aromitas tetrahidroprostaglandinas c16-c20.

2001 
Use of a topical composition for the preparation of a medicament for treating hair loss characterized by: A) an active ingredient selected from the group consisting of a pharmaceutically acceptable prostaglandin F analog having the structure and salts and hydrates analog prostaglandin F; amides, esters, and imides biohidriolizables prostaglandin F analog; optical isomers, diastereomers, and enantiomers of the prostaglandin F analog; and combinations thereof; wherein R1 is selected from the group consisting of CO2H, C (O) NHOH, CO2R5, CH2OH, S (O) 2R5, C (O) NHR 5, C (O) NHS (O) 2R5, and tetrazole; R2 is selected from the group consisting of a hydrogen atom and lower monovalent hydrocarbon group; R3 and R4 each independently selected from the group consisting of H, CH3, C2H5, OR10, SR10, and OH; with the proviso that R3 and R4 are not both OH. R5 is selected from the group consisting of monovalent hydrocarbon groups, monovalent hydrocarbon substituted aromatic groups, substituted aromatic groups, carbocyclic groups, substituted carbocyclic groups, heterogeneous groups, substituted heterogeneous groups, heterocyclic groups, substituted heterocyclic groups, heteroaromatic groups, and groups heteroaromatic substituted; X is selected from the group consisting of NR6R7, OR8, SR9, S (O) R9, and S (O) 2R9. R6, R7, and R8 are each independently selected from the group consisting of hydrogen atoms, acyl groups, monovalent hydrocarbon groups, monovalent hydrocarbon substituted heterogeneous groups, substituted heterogeneous groups, carbocyclic groups, substituted carbocyclic groups, aromatic groups, aromatic groups substituted heteroaromatic groups, and substituted heteroaromatic groups; R9 is selected from the group consisting of monovalent hydrocarbon groups, monovalent hydrocarbon substituted heterogeneous groups, substituted heterogeneous groups, carbocyclic groups, substituted carbocyclic groups, heterocyclic groups, substituted heterocyclic groups, aromatic groups, substituted aromatic groups, heteroaromatic groups, and groups heteroaromatic substituted.
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