Rifabutin-induced severe panuveitis: an unusual case of early onset in a patient with AIDS.

Drug-induced uveitis is a rare condition and usually based on a temporal relationship between drug use and the occurrence of uveitis. Some drugs, such as rifabutin, are well-known causative agents of uveitis. The pathogenesis is unclear, but the disease seems to be associated with direct toxicity. A non-granulomatous anterior uveitis is the most common presentation. Although the prognosis is good, atypically severe cases can occur.