Cytogenetic analysis of 23 Japanese patients with amyotrophic lateral sclerosis

The cytogenetic analysis of 23 Japanese patients with amyotrophic lateral sclerosis is reported. G-banded chromosomes of cultured peripheral blood lymphocytes of one subject had a constitutional chromosomal translocation, t(7;13)(p22;q21). No constitutional chromosome abnormality was found in any of the other 22 Japanese patients with amyotrophic lateral sclerosis tested.