Metabolism of nuclear proteins of the thymus and bone marrow cells in mice with hepatoma 22

: Specific characteristics of nuclear proteins synthesis were studied in thymus and bone marrow cells of mice with solid hepatoma 22, which enabled to find three main periods of alterations in the protein synthesis within 1-3 days, 5-9 and 11-13 days after administration of hepatoma 22. The most distinct alterations were observed within first day after the hepatoma 22 administration, which may be considered as a primary reaction of nuclear apparatus in the cells of tumor-bearing animals.