Percutaneous coronary intervention versus coronary artery bypass grafting in patients with reduced ejection fraction

Objective The aim of this study was to evaluate comparative outcomes for PCI vs CABG in patients with reduced ejection fraction (EF). Methods All patients from the University of Pittsburgh Medical Center from 2011-2018 who had reduced preoperative EF ( Results A total of 2000 patients were included in the current study consisting of CABG (n=1553) and PCI (n=447) cohorts with a mean EF of 35% (+/- 9.53). Propensity matching yielded a 1:1 match with 324 patients in each cohort, controlling for all baseline characteristics. Thirty-day mortality was similar for PCI vs CABG (6.2% vs 4.9%; p=0.49). Overall mortality over the study follow-up period (median 3.23 [1.83-4.98]) was significantly higher for the PCI cohort (37.4% vs 21.3%; p Conclusions Patients with reduced ejection fraction who underwent CABG had significantly improved survival, lower MACCE, and fewer repeat revascularization procedures compared to patients who underwent PCI.