Walk-through survey report of Burns-Biotec Laboratories, Omaha, Nebraska, November 24-25, 1980

In efforts to understand risks to workers engaged in research with recombinant DNA processes and associated industries, a walk-through survey was conducted at Burns-Biotec Laboratories near Omaha, Nebraska. At the facility, human leukocyte interferon production was carried out using recombinant DNA fermentation techniques in facilities separate from other work at the company. Six employees were assigned to the recombinant DNA project; 45 employees worked at the facility. An Institutional Bio-Safety Committee was formed in compliance with National Institutes of Health (NIH) guidelines. Work practices and emergency and accident procedures were reviewed. The authors conclude that Burns-Biotec Laboratories are meeting various relevant safety issues in a responsible manner. Specific recommendations are offered concerning validation procedures, facility design, work practices, and a medical surveillance program.