Advance in the mouse model of hepatitis B virus infection

A brine supply system including a first brine tank to store diluted brine of a predetermined concentration to be supplied into an electrolytic brine treatment device and a second brine tank to store an amount of saturated brine at a predetermined concentration. When the level of diluted brine becomes a lower limit level, the first brine tank is supplied with fresh water from an external supply source of water until the level of diluted brine becomes an upper limit level and is intermittently supplied with a predetermined amount of the saturated brine from the second brine tank. Based on a previously memorized supply time of the fresh water, a supply frequency and a supply interval of the saturated brine for the memorized supply time are calculated to maintain the diluted brine at the predetermined concentration even when the first brine tank is being supplied with the fresh water.