Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier

Roberto Villaseñor,Laurence Ozmen,Nadia Messaddeq,Fiona Grüninger,Hansruedi Loetscher,Annika Keller,Christer Betsholtz,Per-Ola Freskgård,Ludovic Collin

Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier

2016

Roberto Villaseñor
Laurence Ozmen
Nadia Messaddeq
Fiona Grüninger
Hansruedi Loetscher
Annika Keller
Christer Betsholtz
Per-Ola Freskgård
Ludovic Collin

The Blood-Brain Barrier (BBB) restricts access of large molecules to the brain. The low endocytic activity of brain endothelial cells (BECs) is believed to limit delivery of immunoglobulins (IgG) t ...

Keywords:

Antibody
Intracellular
Endogeny
Phosphorylation
Blood–brain barrier
Endocytic cycle
Immunoglobulin G
Cell biology
Medicine
In vivo
Basement membrane
Parenchyma

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations