Studies on Intramolecular Mannich Reaction of (S)-2-(a-Hydroxyethyl)benzimidazole. Synthesis of (1S)-4-Aryl-4,5-dihydro-1-methyl-1H,3H-[1,3,5]oxadiazepino[5,6-a]benzimidazoles — A New Class of Heterocyclic Compounds

Shaheen A. Hussain,T. B. Sarfaraz,Naheed Sultana,Najma Murtaza,Izhar H. Qureshi

Studies on Intramolecular Mannich Reaction of (S)-2-(a-Hydroxyethyl)benzimidazole. Synthesis of (1S)-4-Aryl-4,5-dihydro-1-methyl-1H,3H-[1,3,5]oxadiazepino[5,6-a]benzimidazoles — A New Class of Heterocyclic Compounds

1990

Shaheen A. Hussain
T. B. Sarfaraz
Naheed Sultana
Najma Murtaza
Izhar H. Qureshi

The title reaction of (S)-2-(α-hydroxyethyl)benzimidazole with primary aromatic amines and formaldehyde has been shown to furnish title compounds. The antibacterial activity of these compounds has also been evaluated

Keywords:

Photochemistry
Mannich reaction
Aryl
Benzimidazole
Organic chemistry
Ketone
Biological activity
Intramolecular reaction
Intramolecular force
Formaldehyde
Chemistry

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