The effect of ketamine on shivering in patients undergoing spinal anesthesia
2018
Background: Sever shivering is the most common adverse effect of spinal anesthesia during and
after operation that causes physiologic complication. One of the drugs that could decrease operative
shivering is ketamine.
Objective: The aim of this study is the effect of ketamine to reduce shivering, during spinal
anesthesia.
Methods: This prospective randomized, and double-blind clinical trial was conducted on 355
patients of candida different surgeries with spinal anesthesia in Bu-Ali and Velayat Hospitals in
Qazvin (2017). Patients were randomly divided into experimental (n=175) and control (n=180)
groups. For the experimental and control groups, ketamine (0.2 ml/kg) or an equal volume of
distilled water were administered with intravenous infusion pumps immediately after initiating
spinal anesthesia, respectively. Then degree of shivering checked by anesthesiologist with visual
scale during surgery.
Findings: The rate and intensity of shivering at ketamine group significantly decreased compared to
the control group. Shivering during surgery was less than in men, urological surgery and age (20-40
years) in both groups.
Conclusion: Adding ketamine to drug’s pump in patients undergoing spinal anesthesia could be
effective method to control shivering during operation.
Keywords: Operative shivering, Spinal anesthesia, Ketamine, Intensity of shivering
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