[Changes of Serum Gonadal Hormones Levels During Musk-secreting Period and Estrus of Moschus berezovskii].

Objective: To detect concentrations of serum gonadal hormones( testosterone,estradiol and progesterone) in musk-secreting period and estrus of Moschus berezovskii,and to study the association of serum gonadal hormones concentrations and musksecreting. Methods: The concentrations of serum gonadal hormones were detected with magnetic particle separation ELISA. Results: During musk-secreting period,concentration changes of three serum gonadal hormones showed clear regularity,three crests occurred synchronously. Before musk-secreting period,testosterone,estradiol and progesterone concentrations were at its lower level,in prime musksecreting period,they increased rapidly to respective highest peak; at later musk-secreting period,they quickly dropped to close to its previous levels before musk-secreting period. During estrus,serum testosterone concentration increased to lower peaks than that at later musk-secreting period. Estradiol remained at a low level and progesterone level was closed to zero. Serum testosterone concentrations in prime musk-secreting period were 114. 4 ~ 190. 5 times of estrus. During musk-secreting period,there were significant positive correlation among three serum gonadal hormone levels,a positive correlation between musk yield and serum testosterone levels,and negative correlation of musk yield with serum estradiol and progesterone levels as well as musk deer ages. Conclusion: Serum testosterone concentrations in prime musk-secreting period increase to the highest levels,which can provide reference in musk secretion induced by artificial means.