Iridocorneal Endothelial Syndrome-Clinical Observation and Treatment

Fifteen patients (4 men and 11 women ranged in age from 19 to 70 years) of the iridocorneal endothelial syndrome were reviewed retrospectively in this study. In total 20 eyes, there were 3 eyes with Chandler's syndrome, 14 eyes with progressive iris atrophy and 3 eyes with Cogan-Reese syndrome. The duration of the follow-up was from 6 months to 10 years. Visual disturbance was the most common chief complaint. Specular microscopy revealed corneal endothelial abnormalities in 10 examined eyes. Variable degree of corectopia and peripheral anterior synechia occurred in all eyes. Atrophy of the iris associated with hole formation were described and classified into five groups. Pigment on the anterior lens surface was present in 4 eyes. Penetrating keratoplasty was done in one eye. Trabeculectomy was performed in 6 eyes. Intraocular pressure was well-controlled with or without medication. Two eyes had persistent bullous keratopathy after surgery.