Cerebroprotein hydrolysate in traumatic brain injury

Introduction: Traumatic brain injury (TBI) is the most common cause of death and disability worldwide, especially in young people. Cerebroprotein hydrolysate (CH) exhibits complex neuroprotective and neurotrophic actions and is thus useful in patients of TBI. Here we report a case of TBI, where CH was found helpful in improving the patient’s condition. Case Presentation: A 50 year old male had a road traffic accident and suffered from head injury. Computed tomography of the brain showed right temporal intra parenchymal hemorrhage, right frontal hemorrhagic contusion, subarachnoid hemorrhage in right temporo-parietal region and an undisplaced linear fracture of right squamous temporal bone. After gaining consciousness the patient did not remember anything, and suffered cognitive deficits. Anterograde amnesia secondary to contusional injury was diagnosed, and patient observation for spontaneous recovery of memory was recommended. Even after 20 days post-accident, there was not much improvement in the patient’s condition. Relatives were given an option of trying out injectable CH, which they agreed. CH was started and the patient started showing signs of improvement. On the night prior to the day of discharge, he suffered from right sided hemiplegia whose cause could not be ascertained. Conclusion: Cerebroprotein hydrolysate is a medication that acts at the brain level and provides us with an effective tool for improving levels of activities of daily living in patients of head injury, thereby decreasing their dependence on caregivers. However, further randomized, controlled trials involving large populations are required.