Murine neuroblastoma cells absorb anti-cytoplasmic tetrodotoxin-sensitive protein antibodies

The properties were investigated of polyclonal antibodies obtained by immunizing with a fraction of cytoplasmic glycoproteins forming sodium channels in liposomes. It was shown that these antibodies can be absorbed by intact murine neuroblastoma cells. Graphs plotting intensity of absorption against numbers of absorbant cells follow a characteristic course dependent on life of the cells in culture and serum concentration in the culture medium.